Primary lymphoma of liver : A case report and review of literature

Primary lymphoma of liver (PHL) is a rare condition representing less than 1% of extra nodal lymphomas. In contrast, wide spread Hodgkin's lymphoma involves the liver in more than 50% of patients (1-3). Recently there is an increased frequency of this tumor, especially in the immunocompromised patient (4). PHL is difficult to diagnose and should be considered in the differential diagnosis of solitary or multiple liver lesions especially when alpha-fetoprotein (AFP) and carcino-embrionic antigen (CEA) are normal. Early diagnosis of PHL is important because the prog- nosis appears to be favorable when combination chemotherapy is initiated early (1). We report a case of primary hepatic lymphoma in an elderly patient, admitted to our department, and review the literature.